ゲノム情報科学研究教育機構  アブストラクト
Date Dec 26, 2013
Speaker Dr. Raymond Wan, Research fellow, School of Life Sciences, The Chinese University of Hong Kong
Title Transformations for Compressing Quality Scores of Next Generation Sequencing Data
Abstract In recent years, next generation sequencing has become an important tool in genomics. While much attention is devoted to the new discoveries that are possible using this data, the problem of archiving the data is often taken for granted. In this talk, I will explain some of our approaches to compressing the quality scores of such data. We combine data transformations with existing compression techniques. I will begin with a brief overview of general data compression, followed by a summary of the format of next generation sequencing data. Then, I will show some of the techniques that we've considered and the results from applying them. Afterwards, I will talk briefly about an unrelated project that I was recently involved in which was to develop a pipeline for detecting viral fusion events using next generation sequencing data. These locations represent where a viral genomic sequence has inserted itself into a host (i.e., human) genome. I will describe both our method and present some results from simulated experiments.
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