Note: Each color represent the degree of promiscuity between families.


* Assignments

 1 "amine receptor activity" (GO:0008227) => "Aminergic GPCRs"
 2 "aspartic-type endopeptidase activity" (GO:0004190) => "Aspartylproteases"
 3 "cysteine-type endopeptidase activity" (GO:0004197) => "Cysteineproteases"
 4 "catalytic activity (GO:0003824)" => "Enzymes"
 5 "rhodopsin-like receptor activity" (GO:0001584) => "GPCRs class A"
 6 "secretin-like receptor activity" (GO:0001633) =>"GPCRs class B"
 7 "metabotropic glutamate GABA-B-like receptor activity" (GO:0008067) =>"GPCRs class C"
 8 "hydrolase activity" (GO:0016787) => "Hydrolases"
 9 "ion channel activity" (GO:0005216) => "Ion Channel"
10 "ligand-gated ion channel activity" (GO:0015276) => "Ion Channel-ligandGated"
11 "kinase activity" (GO:0016301) => "Kinases"
12 "metallopeptidase activity" (GO:0008237) => "Metalloproteases"
13 "ligand-dependent nuclear receptor activity" (GO:0004879) => "Nuclear hormone receptors"
14 "oxidoreductase activity" (GO:0016491) => "Oxidoreductases"
15 "phosphoric diester hydrolase activity" (GO:0008081) => "Phosphodiesterases"
16 "peptide receptor activity, G-protein coupled" (GO:0008528) => "Peptide GPCRs"
17 "protein kinase activity" (GO:0004672) => "Protein kinases"
18 "serine-type peptidase activity" (GO:0008236) => "Serine proteases"
19 "transferase activity" (GO:0016740) => "Transferases"


* Subclass reduction rules

catalytic activity > transferase activity

  transferase activity > kinase activity

              kinase activity > protein kinase activity

catalytic activity > oxidoreductase activity
catalytic activity > hydrolase activity 

  hydrolase activity > aspartic-type endopeptidase activity
  hydrolase activity > cysteine-type endopeptidase activity
  hydrolase activity > metallopeptidase activity
  hydrolase activity > phosphoric diester hydrolase activity
  hydrolase activity > serine-type peptidase activity

rhodopsin-like receptor activity > amine receptor activity

ion channel activity > ligand-gated ion channel activity