Research Interst


[1] Molecular Evolutionary Biology

[2] Protein Engineering

[3] Computational Molecular Biology



Our ancestral organisms did not have whole set of proteins that are used by current organisms. During the course of evolution, living organisms have acquired wide variety of proteins through mutational events such as gene duplication. Associated with the events, the functional variety of proteins have increased. Evolution of protein function is regarded as protein engineering managed by the Nature. I'm interested in the mechanism for the evolution of protein function. On the other hand, the evolution of protein function has led the evolution of higher order function such as memory, body plan, and etc. I'd like to find the connection between the evolution of protein function and the evolution of higher order function.


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toh@kuicr.kyoto-u.ac.jp