アブストラクト
| Date | 2:00pm Sep 05, 2019 |
| Speaker | Hongmin Cai Professor of School of Computer Science & Engineering, South China University of Technology, China |
| Title | Identification of gene-drug and multi-omics regulatory modules through integrative analysis |
| Abstract | The emergence of large amounts of genomic, chemical, and pharmacological data provides new opportunities and challenges for cancer research. Identifying multidimensional regulatory modules from omics data through integration analysis allows us to understand the regulatory relationship among omics data from different molecular levels, thereby provides quantitative understanding on the regulatory mechanisms of biological systems. In particularly, identifying gene?drug regulatory modules is not only crucial in providing a comprehensive understanding of the molecular mechanisms of drug action, but is also important in the development of effective treatments for patients. Accurately determine the complex regulatory modules among pharmacogenomic data remains challenging. This report will introduce our latest research progress in identification of both gene-drug regulatory modules and multidimensional regulatory modules. |