アブストラクト
| Date | 14:00-15:00 Sep 25, 2025 |
| Speaker | Sotaro Takano Bioresource Research Center, RIKEN Japan |
| Title | From cells to communities: Elucidating resource niche partitioning shaped by microbial growth strategies from metabolic networks |
| Abstract | Resource use strategies affect individual organism fitness and community fate. Microbes usually exhibit restrained resource use behavior: utilizing only the preferred resources and restricting others. This behavior, understood from optimal enzyme allocation in metabolism, has recently gained attentions as the drivers of resource niche partitioning and coexistence. Our genome-scale metabolic modeling approach recently demonstrated that this strategy can be diversified among microbes but biased to specific phenotypes. This bias in the evolvability is constrained by the topological features of metabolic networks, which limits the possibility of coexistence. In this seminar, I will discuss how the metabolic network shapes the optimal growth strategy of individual microbes and impacts coexistence. |